Andrew Neilson

Bio

Dr. Neilson’s research focuses on the interactions between dietary phytochemicals (particularly flavonoids) and the gut microbiome, and how these interactions influence human health. Of specific interest are the bioactivities of microbial metabolites produced when the gut microbiome metabolizes unabsorbed dietary components. Specific health areas of interest include gut health and metabolic syndrome. Additionally, Dr. Neilson is investigating how individual genetic variability influences the efficacy of dietary phytochemicals for improvement of gut health and metabolic syndrome. Prior to joining PHHI, Dr. Neilson spent 7.5 years as a faculty member at Virginia Tech.

Publications

• Bioavailable Microbial Metabolites of Flavanols Demonstrate Highly Individualized Bioactivity on In Vitro & beta;-Cell Functions Critical for Metabolic Health , METABOLITES (2023)
• Blueberry intervention mitigates detrimental microbial metabolite trimethylamine N-oxide by modulating gut microbes , BIOFACTORS (2023)
• Dietary phenolics and their microbial metabolites are poor inhibitors of trimethylamine oxidation to trimethylamine N-oxide by hepatic flavin monooxygenase 3 , JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2023)
• Gut Microbiota Depletion Using Antibiotics to Investigate Diet-Derived Microbial Metabolites: An Efficient Strategy , MOLECULAR NUTRITION & FOOD RESEARCH (2023)
• In vitro evidences of the globe artichoke antioxidant, cardioprotective and neuroprotective effects , JOURNAL OF FUNCTIONAL FOODS (2023)
• Mechanism of off-color formation in potato chips fried in oil systems containing ascorbic acid as a stabilizer , LWT-FOOD SCIENCE AND TECHNOLOGY (2023)
• Bioaccessibility and intestinal cell uptake of carotenoids and chlorophylls differ in powdered spinach by the ingredient form as measured using in vitro gastrointestinal digestion and anaerobic fecal fermentation models , FOOD & FUNCTION (2022)
• Bioaccessibility, gut microbial metabolism and intestinal transport of phenolics from 100% Concord grape juice and whole grapes are similar in a simulated digestion and fecal fermentation model , FOOD & FUNCTION (2022)
• Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022)
• Effect of processing on the anti-inflammatory efficacy of cocoa in a high fat diet-induced mouse model of obesity , JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2022)