Andrew Neilson

Bio

Dr. Neilson’s research focuses on the interactions between dietary phytochemicals (particularly flavonoids) and the gut microbiome, and how these interactions influence human health. Of specific interest are the bioactivities of microbial metabolites produced when the gut microbiome metabolizes unabsorbed dietary components. Specific health areas of interest include gut health and metabolic syndrome. Additionally, Dr. Neilson is investigating how individual genetic variability influences the efficacy of dietary phytochemicals for improvement of gut health and metabolic syndrome. Prior to joining PHHI, Dr. Neilson spent 7.5 years as a faculty member at Virginia Tech.

Publications

• Bioaccessibility and intestinal cell uptake of carotenoids and chlorophylls differ in powdered spinach by the ingredient form as measured using in vitro gastrointestinal digestion and anaerobic fecal fermentation models , FOOD & FUNCTION (2022)
• Bioaccessibility, gut microbial metabolism and intestinal transport of phenolics from 100% Concord grape juice and whole grapes are similar in a simulated digestion and fecal fermentation model , FOOD & FUNCTION (2022)
• Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022)
• Effect of processing on the anti-inflammatory efficacy of cocoa in a high fat diet-induced mouse model of obesity , JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2022)
• Enhancing the Cognitive Effects of Flavonoids With Physical Activity: Is There a Case for the Gut Microbiome? , FRONTIERS IN NEUROSCIENCE (2022)
• Microbial Metabolites of Flavanols in Urine are Associated with Enhanced Anti-Proliferative Activity in Bladder Cancer Cells In Vitro , NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2022)
• Phenolic-rich beverages reduce bacterial TMA formation in an ex vivo-in vitro colonic fermentation model , FOOD & FUNCTION (2022)
• Potential of Phenolic Compounds and Their Gut Microbiota-Derived Metabolites to Reduce TMA Formation: Application of an In Vitro Fermentation High-Throughput Screening Model , JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2022)
• An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder , SCIENTIFIC REPORTS (2021)
• Diet-induced obesity in genetically diverse collaborative cross mouse founder strains reveals diverse phenotype response and amelioration by quercetin treatment in 129S1/SvImJ, PWK/EiJ, CAST/PhJ, and WSB/EiJ mice , JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2021)