The Research Technician position in the Kay lab will support funded projects of government, industry and commodity sponsored programs. The position will be responsible for identifying phytochemical/small molecule metabolites. The position will also be expected to take on routine laboratory tasks, as well as task relative to HPLC-MS/MS analysis of plant, and animal and human samples.
This position requires:
- Knowledge and skills to operate HPLC-MS/MS.
- Use of software for operation and data acquisition.
- Safe chemical/sample handling/preparation of reagents for analysis.
- Preparation of analytical standards for HPLC-MS/MS analysis.
- Familiarity with the use of equipment in support of a HPLC-MS/MS, including safe use of fume hoods, storage of chemicals etc.
- Proficiency in MS Office Suite or similar software.
Preferred education, experience and skills include a Bachelors Degree or equivalent combination of training and experience; experience with SCIEX MS platforms; use of extraction methodology; and use of automated processing/fluid handling platforms.
POSTDOC RESEARCH SCHOLAR
The Esposito Lab at Plants for Human Health Institute uses a wide range of Nutraceutical (Functional Foods and Edible Plants) and Cosmeceutical approaches to investigate the interactions of bio-actives found in fruits and vegetables, with a particular focus on regenerative medicine and cosmetic applications. Research plans are aimed at studying the systemic architecture that controls inflammation and tissue regeneration processes and investigating proteins or small molecules with novel health benefits with fundamental and applied relevance to muscle health and skin care.
This Postdoc position will contribute to preclinical characterization of molecules in cell culture and animal models. Will also be responsible for training and supervising students and visiting scholars. Will co-author publications, presentations and grant applications.
PhD or equivalent doctorate (e.g., M.D., D.V.M., Sc.D.) in medicinal chemistry, pharmaceutical sciences, animal science or related fields, must have been awarded no more than five years from the initial date of postdoctoral appointment. Must have experience with RT-PCR, qPCR, microscopy, bioactivity-guided isolation, and HPLC. Position requires experience with animal models and rodent model systems.
The ideal candidate will have at least three years of relevant experience with a broad, interdisciplinary knowledge base in the areas of chemistry, biochemistry, and plant biology, a proven track record for independent research and publications, experience with mammalian cell culture, and be highly proficient in a broad range of molecular and biochemical techniques including cell culture, cryopreservation, cytotoxicity assays, microscopy, RT-PCR, qPCR.
PHD CANDIDATE – PINEAPPLE GENOMICS AND METABOLOMICS
We are seeking a highly motivated PhD student to join the Plant Pathways Elucidation Project (www.p2ep.org) based at the North Carolina Research Campus in Kannapolis, NC. The successful candidate will be enrolled in NC State University’s Department of Horticultural Science, and its PhD program will include a minor in Nutrition. The PhD program will be partially supported through the Dole Nutrition Research Institute.
Within the P2EP team, the PhD student will establish genomic resources and develop new genomic tools for the pineapple crop, and use these assets to 1) characterize pathways that lead to important metabolites accumulated in pineapple and 2) determine the genetic basis of resistance to relevant fungal diseases and/or nematodes. Dole has access to a vast range of pineapple biodiversity to facilitate this research quest, and these plant materials will be fully available to the selected candidate.
Start date – Spring 2017
For further information or to apply, contact: Dr. Massimo Iorizzo, Department of Horticultural Science, Plants for Human Health Institute, North Carolina State University
P2EP SUMMER INTERN
The 11-week P2EP summer internship program provides undergraduate students chances to participate and gain research experiences in a multidisciplinary and cross-institutional collaboration environment. Interns are mentored by NCRC faculty members, scientists from industry partners on campus, and by a team of PhD students. Interns participate in weekly meetings, collaborative research, professional development, and educational activities.
P2EP is a one-of-a-kind opportunity for students to discover and characterize plant fibers and phytochemical metabolites along with the pathways that create them. Interns will be exposed to cutting-edge bioinformatics tools, genome sequencing and state-of-the-art facilities, while better preparing themselves for successful careers in the burgeoning STEM fields.