Diabetes

Defined
A group of disease that result in to much sugar in the blood. Type 2 diabetes is impacted by the way the body processes blood sugar. Type 1 diabetes is a chronic condition where the pancreas produces little to no insulin.

Body System of Interest
Endocrine System

PHHI Research
Blackberries
The high antioxidant content and phenolic content and the ability to decrease enzyme activity related to improved glucose utilization, bioactive anthocyanins and proanthocyanidin compounds present in the fermented blueberry-blackberry beverages may act synergistically to reduce risk factors for chronic inflammatory diseases, especially type 2 diabetes.

Blueberries
Our present findings demonstrate that blueberry-polyphenol enriched defatted soybean flour has beneficial effects on blood glucose, body weight, and serum cholesterol and may be useful for the prevention and/or management of metabolic syndrome and diabetes.

Cinnamon
Data from this study suggest that supplementation with aqueous cinnamon extract or cinnamon polyphenol enriched food matrixes show promise in managing glucose homeostasis.

Grapes
The data indicate that grape pomace- soy protein isolate retains and possibly amplifies that health benefits of grape polyphenols which excluding the glycemic sugars present in fresh and processed grapes. Such dietary intervention offers a practical approach to address the growing global incidence of metabolic disorders such as metabolic syndrome and type 2 diabetes, properly controlled and executed clinical trials are needed to demonstrate the value of grape pomace- soy protein isolate as a therapeutically useful functional food ingredient.

Maqui Berries
ANC is an anthocyanin-rich formulation from Maqui Berry which improves hyperglycemic and insulin resistance in obese hyperglycemic mice fed a high fat diet.

Mustard Greens/Broccoli/Cabbage
We observed that mustard greens/broccoli/cabbage, foods that are rich in brassinosteroids, had positive effects upon homobrassinolides administration on some components of the insulin-signaling pathway. The stimulatory effect of homobrassinolides on glucose metabolism subsequently translates into a whole body insulin-sensitizing effect such as improved glucose tolerance.

Quinoa
Quinoa leachate production leaves behind mostly intact quinoa seeds that still contain majority of their macronutrients, which can be recycled as food ingredients. Therefore, quinoa seed leaching may be a way to harness the clinically therapeutic benefits of quinoa phytochemicals while preserving the nutritional benefits of non-leached quinoa components.

Seaweed
Traditionally consumed Alaskan seaweed, particularly brown kelps, evidenced a pronounced inhibitory effect on cabolytic enzyme activity. Thus, these species have potential as natural sources of anti-diabetic agents that could reduce post-prandial hyperglycemia.

Watermelon
Results of this study demonstrate for the first time to our knowledge a beneficial effect of oral administration of watermelon pomace juice on increasing the mass of brown adipose tissue, reducing excess white fat mass and serum concentrations of risk factors for cardiovascular disease, and enhancing NO-dependent vessel reactivity in ZDF rats. Consumption of this functional food may represent a useful strategy for the dietary management of the metabolic syndrome in NIDDM and obesity.